Liquid cell transmission electron microscopy (LC-TEM) is a cutting-edge imaging technique to investigate dynamic phenomena in liquid environments.
This project will use LC-TEM imaging methods to study infectious dynamics in solution. Visualizing host-pathogen interactions is critical to developing a fundamental understanding of the biological processes occurring at the molecular level during infection. The aim is to develop image modalities that will enable improved contrast and resolution to observe viral infectious pathways in real-time.
The project will be based at the Rosalind Franklin Institute where dedicated instrumentation for liquid imaging is constructed. The work is to be conducted in close collaboration with the Division of Structural Biology (STRUBI).