In this study we examine the behavior of ZnO and CuO crystalline nanoparticles trapped within graphene folds while being irradiated with the imaging electron beam from a transmission electron microscope using an acceleration voltage of 80 kV. While trapped in the graphene folds the nanoparticles are relatively stable (as compared to particles residing on the surface of graphene), however the edges are seen to become amorphous. Eventually ruptures form at the edge of a graphene fold and the nano-crystals are observed, in situ, to effuse through the rupture. The transfer of mass from within a fold to the exterior is attributed to the gliding of shortlived vacancies and dislocations which occur at a rate to fast for one to observe. In the case of a ZnO nano-particle as it emerges on the outside of a fold and as the graphene erodes to form a pore the ZnO material spreads out and restructures from a wurtzite crystalline phase to the of a graphene-like phase. Later as ZnO material is sputtered away the materials restructures to different wurtzite phases.
