Molecular imaging and theoretical modelling of 2D nucleotide base networks
Prof Martin Castell
Dr Chris Patrick
Molecular imaging and theoretical modelling of 2D nucleotide base networks
This is a joint experiment / theory project that will suit a student willing to take on the challenge of mastering scanning tunnelling microscopy (STM) and density functional theory (DFT) modelling. 2D molecular networks will be synthesised in ultrahigh vacuum through self-assembly on metal surfaces such as Au(111). STM is used to investigate the ordering of the molecules. DFT is then employed to calculate the relative energies of viable network configurations to gain further insights into the physical interactions that drive self-assembly. Of particular interest are interactions that influence the chirality (handedness) of the molecular arrangements. Examples of this are networks that consist of DNA and RNA nucleobases such as adenine and uracil. This project is relevant to the broader issue of the physical mechanisms that are responsible for the ordering of biomolecules such as nucleotide bases and amino acids. Within this context the project will contribute to the field of abiogenesis.
The description above outlines a possible new research project being offered to prospective new postgraduate students.
For full details of all postgraduate research projects available for new students and how to apply, please see postgraduate projects available.
Note that post-doctoral research positions are advertised under "Work with Us"