Investigation of atomic structures of bioactive glasses for biomedical applications

Bioactive glasses play a key role in bone tissue engineering due to their ability to form strong bond with the living tissues . This is often related to the ability of such glasses to precipitate bone-compatible hydroxyapatite phasesat rhe surface. It is also  observed that their bioactivity can be modified by various additives or dopants. However, the mechanisms of the hydroxyapatite formation and the influence of dopants/additives and composition of the glass on  hydroxyapatite precipitation are poorly understood. This is in part related to the fact that there is no reliable experimental information on structures of such glasses. In the project we will study the atomic structures of various bioactive glasses prepared by different methods and containing different additives using advanced electron selected area and nanodiffraction, reduced density function (RDF) analysis, imaging and modelling methods.

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